Issue

Vol. 12 (2020)

Mussel‑Inspired Redox‑Active and Hydrophilic Conductive Polymer Nanoparticles for Adhesive Hydrogel Bioelectronics

https://doi.org/10.1007/s40820-020-00507-0
Donglin Gan
Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People’s Republic of China
Tao Shuai
Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People’s Republic of China
Xiao Wang
Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People’s Republic of China
Ziqiang Huang
Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People’s Republic of China
Fuzeng Ren
Department of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, Guangdong, People’s Republic of China
Liming Fang
Department of Polymer Science and Engineering, School of Materials Science and Engineering, South China University of Technology, Guangzhou, People’s Republic of China
Kefeng Wang
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, People’s Republic of China
Chaoming Xie
Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People’s Republic of China
Xiong Lu
Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People’s Republic of China

Corresponding Author: Xiong Lu

luxiong_2004@163.com

Nano-Micro Letters, Vol. 12 (2020), Article Number: 169

Abstract

Conductive polymers (CPs) are generally insoluble, and developing hydrophilic CPs is significant to broaden the applications of CPs. In this work, a mussel-inspired strategy was proposed to construct hydrophilic CP nanoparticles (CP NPs), while endowing the CP NPs with redox activity and biocompatibility. This is a universal strategy applicable for a series of CPs, including polyaniline, polypyrrole, and poly(3,4-ethylenedioxythiophene). The catechol/quinone contained sulfonated lignin (LS) was doped into various CPs to form CP/LS NPs with hydrophilicity, conductivity, and redox activity. These CP/LS NPs were used as versatile nanofillers to prepare the conductive hydrogels with long-term adhesiveness. The CP/LS NPs-incorporated hydrogels have a good conductivity because of the uniform distribution of the hydrophilic NPs in the hydrogel network, forming a well-connected electric path. The hydrogel exhibits long-term adhesiveness, which is attributed to the mussel-inspired dynamic redox balance of catechol/quinone groups on the CP/LS NPs. This conductive and adhesive hydrogel shows good electroactivity and biocompatibility and therefore has broad applications in electrostimulation of tissue regeneration and implantable bioelectronics.


Highlights:


1 A universal strategy was proposed to producing conductive, redox-active, and hydrophilic sulfonated lignin-conductive polymer nanoparticles (CP/LS NPs).
2 By incorporating the CP/LS NPs into hydrogel network, a good conductive, adhesive, and tough hydrogel was obtained.
3 The redox-active NPs maintained enough catechol groups inner the hydrogel for adhesiveness.

Keywords

Mussel-inspired Redox-active nanoparticles Conductive polymer Conductive hydrogel Adhesive bioelectronics
Gan, Donglin, Tao Shuai, Xiao Wang, Ziqiang Huang, Fuzeng Ren, Liming Fang, Kefeng Wang, Chaoming Xie, and Xiong Lu. 2020. “Mussel‑Inspired Redox‑Active and Hydrophilic Conductive Polymer Nanoparticles for Adhesive Hydrogel Bioelectronics”. Nano-Micro Letters 12 (August):169. https://doi.org/10.1007/s40820-020-00507-0.
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