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Vol. 5 No. 3 (2013)

Indocyanine Green Nanoparticles for Theranostic Applications

https://doi.org/10.1007/BF03353743
Zonghai Sheng
Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Dehong Hu
Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Miaomiao Xue
Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Meng He
Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Ping Gong
Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
Lintao Cai
Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China

Corresponding Author: Lintao Cai

lt.cai@siat.ac.cn

Nano-Micro Letters, Vol. 5 No. 3 (2013), Article Number: 145-150

Abstract

Theranostics is a concept that integrated imaging and therapy. As an emerging field, it embraces multiple techniques to arrive at an individualized treatment purpose. Indocyanine green (ICG) is a near infrared dye that has been approved by Food and Drug Administration (FDA) in USA for the use in indicator-dilution studies in humans. ICG nanoparticles (NPs) have attracted much attention for its potential applications in cancer theranostics. This review focuses on the preparation, application of ICG NPs for in vivo imaging (fluorescent imaging and photoacoustic imaging) and therapeutics (photothermal therapy, photodynamic therapy and photoacoustic therapy), and future directions based on recent developments in these areas. It is hoped that this review might provide new impetus to understand ICG NPs for cancer theranostics.

Keywords

Indocyanine green (ICG) Nanoparticles Theranostics Cancer
Sheng, Zonghai, Dehong Hu, Miaomiao Xue, Meng He, Ping Gong, and Lintao Cai. 2013. “Indocyanine Green Nanoparticles for Theranostic Applications”. Nano-Micro Letters 5 (3):145-50. https://doi.org/10.1007/BF03353743.
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