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Vol. 8 No. 3 (2016)

Biomedical Perspective of Electrochemical Nanobiosensor

https://doi.org/10.1007/s40820-015-0077-x
Priti Singh
Department of Biotechnology, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh 211004, India
Shailendra Kumar Pandey
Department of Chemical Engineering, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh 211004, India
Jyoti Singh
Department of Biotechnology, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh 211004, India
Sameer Srivastava
Department of Biotechnology, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh 211004, India
Sadhana Sachan
Department of Chemical Engineering, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh 211004, India
Sunil Kumar Singh
Department of Biotechnology, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh 211004, India

Corresponding Author: Sunil Kumar Singh

singh.sunil06@gmail.com

Nano-Micro Letters, Vol. 8 No. 3 (2016), Article Number: 193-203

Abstract

Electrochemical biosensor holds great promise in the biomedical area due to its enhanced specificity, sensitivity, label-free nature and cost effectiveness for rapid point-of-care detection of diseases at bedside. In this review, we are focusing on the working principle of electrochemical biosensor and how it can be employed in detecting biomarkers of fatal diseases like cancer, AIDS, hepatitis and cardiovascular diseases. Recent advances in the development of implantable biosensors and exploration of nanomaterials in fabrication of electrodes with increasing the sensitivity of biosensor for quick and easy detection of biomolecules have been elucidated in detail. Electrochemical-based detection of heavy metal ions which cause harmful effect on human health has been discussed. Key challenges associated with the electrochemical sensor and its future perspectives are also addressed.

Keywords

Biomarkers Point-of-care detection Nanomaterials Electroactive species Potentiometric Amperometric Implantable
Singh, Priti, Shailendra Kumar Pandey, Jyoti Singh, Sameer Srivastava, Sadhana Sachan, and Sunil Kumar Singh. 2015. “Biomedical Perspective of Electrochemical Nanobiosensor”. Nano-Micro Letters 8 (3):193-203. https://doi.org/10.1007/s40820-015-0077-x.
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