Issue

Vol. 9 No. 1 (2017)

Fabrication and Applications of Micro/Nanostructured Devices for Tissue Engineering

https://doi.org/10.1007/s40820-016-0103-7
Tania Limongi
SMILEs Lab, Physical Science and Engineering (PSE) and Biological and Environmental Sciences and Engineering (BESE) Divisions, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia
Luca Tirinato
SMILEs Lab, Physical Science and Engineering (PSE) and Biological and Environmental Sciences and Engineering (BESE) Divisions, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia
Francesca Pagliari
Department of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia
Andrea Giugni
SMILEs Lab, Physical Science and Engineering (PSE) and Biological and Environmental Sciences and Engineering (BESE) Divisions, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia
Marco Allione
SMILEs Lab, Physical Science and Engineering (PSE) and Biological and Environmental Sciences and Engineering (BESE) Divisions, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia
Gerardo Perozziello
Laboratory of Nanotechnology BioNEM, Department of Experimental and Clinical Medicine, University ‘‘Magna Graecia’’ of Catanzaro, Viale Europa - Loc. Germaneto, 88100 Catanzaro, Italy
Patrizio Candeloro
Laboratory of Nanotechnology BioNEM, Department of Experimental and Clinical Medicine, University ‘‘Magna Graecia’’ of Catanzaro, Viale Europa - Loc. Germaneto, 88100 Catanzaro, Italy
Enzo Di Fabrizio
SMILEs Lab, Physical Science and Engineering (PSE) and Biological and Environmental Sciences and Engineering (BESE) Divisions, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia

Corresponding Author: Tania Limongi

tania.limongi@kaust.edu.sa

Nano-Micro Letters, Vol. 9 No. 1 (2017), Article Number: 1

Abstract

Nanotechnology allows the realization of new materials and devices with basic structural unit in the range of 1–100 nm and characterized by gaining control at the atomic, molecular, and supramolecular level. Reducing the dimensions of a material into the nanoscale range usually results in the change of its physiochemical properties such as reactivity, crystallinity, and solubility. This review treats the convergence of last research news at the interface of nanostructured biomaterials and tissue engineering for emerging biomedical technologies such as scaffolding and tissue regeneration. The present review is organized into three main sections. The introduction concerns an overview of the increasing utility of nanostructured materials in the field of tissue engineering. It elucidates how nanotechnology, by working in the submicron length scale, assures the realization of a biocompatible interface that is able to reproduce the physiological cell–matrix interaction. The second, more technical section, concerns the design and fabrication of biocompatible surface characterized by micro- and submicroscale features, using microfabrication, nanolithography, and miscellaneous nanolithographic techniques. In the last part, we review the ongoing tissue engineering application of nanostructured materials and scaffolds in different fields such as neurology, cardiology, orthopedics, and skin tissue regeneration.

Keywords

Nanomaterials Nanostructures Microfabrication Nanofabrication Device Tissue engineering
Limongi, Tania, Luca Tirinato, Francesca Pagliari, Andrea Giugni, Marco Allione, Gerardo Perozziello, Patrizio Candeloro, and Enzo Di Fabrizio. 2016. “Fabrication and Applications of Micro/Nanostructured Devices for Tissue Engineering”. Nano-Micro Letters 9 (1):1. https://doi.org/10.1007/s40820-016-0103-7.
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References
  1. J. Hwang, Y. Jeong, J.M. Park, K.H. Lee, J.W. Hong, J. Choi, Biomimetics: forecasting the future of science, engineering, and medicine. Int. J. Nanomed. 8(10), 5701–5713 (2015). doi:10.2147/IJN.S83642
  2. M.J. Webber, E.A. Appel, E.W. Meijer, R. Langer, Supramolecular biomaterials. Nat. Mater. 15(1), 13–26 (2015). doi:10.1038/nmat4474
  3. T.U. Luu, S.C. Gott, B.W. Woo, M.P. Rao, W.F. Liu, Micro- and nanopatterned topographical cues for regulating macrophage cell shape and phenotype. ACS Appl. Mater. Interfaces 7(51), 28665–28672 (2015). doi:10.1021/acsami.5b10589
  4. N. Mauro, A. Manfredi, E. Ranucci, P. Procacci, M. Laus, D. Antonioli, C. Mantovani, V. Magnaghi, P. Ferruti, Degradable poly(amidoamine) hydrogels as scaffolds for in vitro culturing of peripheral nervous system cells. Macromol. Biosci. 13(3), 332–347 (2013). doi:10.1002/mabi.201200354
  5. W. Zhu, C. O’Brien, J.R. O’Brien, L.G. Zhang, 3D nano/microfabrication techniques and nanobiomaterials for neural tissue regeneration. Nanomedicine 9(6), 859–875 (2014). doi:10.2217/nnm.14.36
  6. P. Haisheng, L. Xunpei, W. Ran, J. Feng, D. Liang, W. Qun, Emerging nanostructured materials for musculoskeletal tissue engineering. J. Mater. Chem. B 2(38), 6435–6461 (2014). doi:10.1039/c4tb00344f
  7. H. Park, C. Cannizzaro, G. Vunjak-Novakovic, R. Langer, C.A. Vacanti, O.C. Farokhzad, Nanofabrication and microfabrication of functional materials for tissue engineering. Tissue Eng. 13(8), 1867–1877 (2007). doi:10.1089/ten.2006.0198
  8. B.N. Brown, B.D. Ratner, S.B. Goodman, S. Amar, S.F. Badylak, Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine. Biomaterials 33(15), 3792–3802 (2012). doi:10.1016/j.biomaterials.2012.02.034
  9. B.D. Ratner, S.J. Bryant, Biomaterials: where we have been and where we are going. Annu. Rev. Biomed. Eng. 6, 41–75 (2004). doi:10.1146/annurev.bioeng.6.040803.140027
  10. M. Veiseh, A. Nikjoo, E.A. Turley, M.J. Bissell, Nanotechnology and regenerative engineering: the scaffold: from microenvironment to nanoenvironment: ultrastructure and function of extracellular matrix, ed. by C.T. Laurencin, L.S. Nair (CRC Press, Boca Raton, 2015), pp 39–62
  11. F. Gattazzo, A. Urciuolo, P. Bonaldo, Extracellular matrix: a dynamic microenvironment for stem cell niche. Biochim. Biophys. Acta 1840(8), 2506–2519 (2014). doi:10.1016/j.bbagen.2014.01.010
  12. R.G. Flemming, C.J. Murphy, G.A. Abrams, S.L. Goodman, P.F. Nealey, Effects of synthetic micro- and nano-structured surfaces on cell behavior. Biomaterials 20(6), 573–588 (1999)
  13. F. Gentile, R. La Rocca, G. Marinaro, A. Nicastri, A. Toma et al., Differential cell adhesion on mesoporous silicon substrates. ACS Appl. Mater. Interfaces 4(6), 2903–2911 (2012). doi:10.1021/am300519a
  14. F. Gentile, L. Tirinato, E. Battista, F. Causa, C. Liberale, E.M. di Fabrizio, P. Decuzzi, Cells preferentially grow on rough substrates. Biomaterials 31(28), 7205–7212 (2010). doi:10.1016/j.biomaterials.2010.06.016
  15. T. Limongi, F. Cesca, F. Gentile, R. Marotta, R. Ruffilli et al., Nanostructured superhydrophobic substrates trigger the development of 3d neuronal networks. Small 9(3), 402–412 (2013). doi:10.1002/smll.201201377
  16. F. Cesca, T. Limongi, A. Accardo, A. Rocchi, M. Orlando, V. Shalabaeva, E. Di Fabrizio, F. Benfenati, Fabrication of biocompatible free-standing nanopatterned films for primary neuronal cultures. RSC Adv. 4(86), 45696–45702 (2014). doi:10.1039/c4ra08361j
  17. T. Limongi, R. Schipani, A. Di Vito, A. Giugni, M. Francardi et al., Photolithography and micromolding techniques for the realization of 3D polycaprolactone scaffolds for tissue engineering applications. Microelectron. Eng. 141, 135–139 (2015). doi:10.1016/j.mee.2015.02.030
  18. T. Limongi, E. Miele, V. Shalabaeva, R. La Rocca, R. Schipani et al., Development, characterization and cell cultural response of 3d biocompatible micro-patterned poly-ε-caprolactone scaffolds designed and fabricated integrating lithography and micromolding fabrication techniques. J. Tissue Sci. Eng. 6(1), 5 (2015). doi:10.4172/2157-7552.1000145
  19. K.M. Ainslie, T.A. Desai, Microfabricated implants for applications in therapeutic delivery, tissue engineering, and biosensing. Lab Chip 8(11), 1864–1878 (2008). doi:10.1039/b806446f
  20. C.W. Park, Y.S. Rhee, S.H. Park, S.D. Danh, S.H. Ahn, S.C. Chi, E.S. Park, In vitro/in vivo evaluation of NCDS-micro-fabricated biodegradable implant. Arch. Pharm. Res. 33(3), 427–432 (2010). doi:10.1007/s12272-010-0312-4
  21. A.S. Curtis, C.D. Wilkinson, J. Crossan, C. Broadley, H. Darmani, K.K. Johal, H. Jorgensen, W. Monaghan, An in vivo microfabricated scaffold for tendon repair. Eur. Cell Mater. 9, 50–57 (2005)
  22. D. Shi, X. Xu, Y. Ye, K. Song, Y. Cheng, J. Di, Q. Hu, J. Li, H. Ju, Q. Jiang, Z. Gu, Photo-cross-linked scaffold with kartogenin-encapsulated nanoparticles for cartilage regeneration. ACS Nano 10(1), 1292–1299 (2016). doi:10.1021/acsnano.5b06663
  23. K. Baranes, M. Shevach, O. Shefi, T. Dvir, Gold nanoparticle-decorated scaffolds promote neuronal differentiation and maturation. Nano Lett. 16(5), 2916–2920 (2015). doi:10.1021/acs.nanolett.5b04033
  24. E.L. Hopley, S. Salmasi, D.M. Kalaskar, A.M. Seifalian, Carbon nanotubes leading the way forward in new generation 3D tissue engineering. Biotechnol. Adv. 32(5), 1000–1014 (2014). doi:10.1016/j.biotechadv.2014.05.003
  25. A. Childs, U.D. Hemraz, N.J. Castro, H. Fenniri, L.G. Zhang, Novel biologically-inspired rosette nanotube PLLA scaffolds for improving human mesenchymal stem cell chondrogenic differentiation. Biomed. Mater. 8(6), 065003 (2013). doi:10.1088/1748-6041/8/6/065003
  26. Y.C. Shin, J.H. Lee, M.J. Kim, S.W. Hong, B. Kim, J.K. Hyun, Y.S. Choi, J.C. Park, D.W. Han, Stimulating effect of graphene oxide on myogenesis of C2C12 myoblasts on RGD peptide-decorated PLGA nanofiber matrices. J. Biol. Eng. 9, 22 (2015). doi:10.1186/s13036-015-0020-1
  27. A. Raspa, A. Marchini, R. Pugliese, M. Mauri, M. Maleki, R. Vasita, F. Gelain, A biocompatibility study of new nanofibrous scaffolds for nervous system regeneration. Nanoscale 8(1), 253–265 (2015). doi:10.1039/C5NR03698D
  28. J.M. Szymanski, Q. Jallerat, A.W. Feinberg, ECM protein nanofibers and nanostructures engineered using surface-initiated assembly. J. Vis. Exp. 86, e51176 (2014). doi:10.3791/51176
  29. C. Mota, S. Danti, D. D’Alessandro, L. Trombi, C. Ricci et al., Multiscale fabrication of biomimetic scaffolds for tympanic membrane tissue engineering. Biofabrication 7(2), 025005 (2015). doi:10.1088/1758-5090/7/2/025005
  30. E. Zanchetta, E. Guidi, G. Della Giustina, M. Sorgato, M. Krampera et al., Injection molded polymeric micropatterns for bone regeneration study. ACS Appl. Mater. Interfaces 7(13), 7273–7281 (2015). doi:10.1021/acsami.5b00481
  31. R.E. McMahon, X. Qu, A.C. Jimenez-Vergara, C.A. Bashur, S.A. Guelcher, A.S. Goldstein, M.S. Hahn, Hydrogel-electrospun mesh composites for coronary artery bypass grafts. Tissue Eng. C 17(4), 451–461 (2011). doi:10.1089/ten.tec.2010.0427
  32. M.J. Lima, V.M. Correlo, R.L. Reis, Micro/nano replication and 3D assembling techniques for scaffold fabrication. Mater. Sci. Eng. Part C 42, 615–621 (2014). doi:10.1016/j.msec.2014.05.064
  33. V. Raffa, O. Vittorio, V. Pensabene, A. Menciassi, P. Dario, FIB-nanostructured surfaces and investigation of Bio/nonbio interactions at the nanoscale. IEEE Trans. Nanobiosci. 7(1), 1–10 (2008). doi:10.1109/TNB.2008.2000143
  34. F. De Angelis, C. Liberale, M.L. Coluccio, G. Cojoc, E. Di Fabrizio, Emerging fabrication techniques for 3D nano-structuring in plasmonics and single molecule studies. Nanoscale 3(7), 2689–2696 (2011). doi:10.1039/c1nr10124b
  35. B.D. Gates, Q. Xu, M. Stewart, D. Ryan, C.G. Willson, G.M. Whitesides, New approaches to nanofabrication: molding, printing, and other techniques. Chem. Rev. 105(4), 1171–1196 (2005). doi:10.1021/cr030076o
  36. J.C. Love, B.W. Daniel, M.W. George, Dekker Encyclopedia of Nanoscience and Nanotechnology—Six Volume Set (Print Version) (CRC Press, 2004). doi:10.1201/9781439834398.ch174
  37. C.J. Bettinger, K.M. Cyr, A. Matsumoto, R. Langer, J.T. Borenstein, D.L. Kaplan, Silk fibroin microfluidic devices. Adv. Mater. 19(5), 2847–2850 (2007). doi:10.1002/adma.200602487
  38. A. Paguirigan, D.J. Beebe, Gelatin based microfluidic devices for cell culture. Lab Chip 6(3), 407–413 (2006). doi:10.1039/b517524k
  39. L. Robert, J.B. Christopher, T.B. Jeffrey, in Nanotechnology and Tissue Engineering (CRC Press, 2008), pp. 87–119. doi:10.1201/9781420051834.ch4
  40. A. Brown, G.A. Burke, B.J. Meenan, Patterned cell culture substrates created by hot embossing of tissue culture treated polystyrene. J. Mater. Sci. Mater. Med. 24(12), 2797–2807 (2013). doi:10.1007/s10856-013-5011-5
  41. A.R. Jung, R.Y. Kim, H.W. Kim, K.R. Shrestha, S.H. Jeon, K.J. Cha, Y.H. Park, D.S. Kim, J.Y. Lee, Nanoengineered polystyrene surfaces with nanopore array pattern alters cytoskeleton organization and enhances induction of neural differentiation of human adipose-derived stem cells. Tissue Eng. A 21(13–14), 2115–2124 (2015). doi:10.1089/ten.tea.2014.0346
  42. P.M. Mendes, Cellular nanotechnology: making biological interfaces smarter. Chem. Soci. Rev. 42(24), 9207–9218 (2013). doi:10.1039/c3cs60198f
  43. MathSciNet
  44. D. Kluge, J.C. Singer, B.R. Neugirg, J.W. Neubauer, H.-W. Schmidt, A. Fery, Top–down meets bottom–up: a comparison of the mechanical properties of melt electrospun and self-assembled 1,3,5-benzenetrisamide fibers. Polymer 53(25), 5754–5759 (2012). doi:10.1016/j.polymer.2012.10.016
  45. G. Luo, K.S. Teh, Y. Liu, X. Zang, Z. Wen, L. Lin, Direct-write, self-aligned electrospinning on paper for controllable fabrication of three-dimensional structures. ACS Appl. Mater. Interfaces 7(50), 27765–27770 (2015). doi:10.1021/acsami.5b08909
  46. P.K. Chu, J.Y. Chen, L.P. Wang, N. Huang, Plasma-surface modification of biomaterials. Mater. Sci. Eng. R 36(5–6), 143–206 (2002). doi:10.1016/S0927-796X(02)00004-9
  47. F. Kantawong, R. Burchmore, N. Gadegaard, R.O.C. Oreffo, M.J. Dalby, Proteomic analysis of human osteoprogenitor response to disordered nanotopography. J. R. Soc. Interface 6(40), 1075–1086 (2009). doi:10.1098/rsif.2008.0447
  48. W.A. Loesberg, J. te Riet, F.C. van Delft, P. Schon, C.G. Figdor, S. Speller, J.J. van Loon, X.F. Walboomers, J.A. Jansen, The threshold at which substrate nanogroove dimensions may influence fibroblast alignment and adhesion. Biomaterials 28(27), 3944–3951 (2007). doi:10.1016/j.biomaterials.2007.05.030
  49. K. Chung, J.A. DeQuach, K.L. Christman, Nanopatterned interfaces for controlling cell behavior. Nano LIFE 1(2), 63–77 (2010). doi:10.1142/S1793984410000055
  50. M. Benjamin, S. M. Gregory, in Nanotechnology and Tissue Engineering (CRC Press, 2008), pp. 261–282. doi:10.1201/9781420051834.ch10
  51. A.T. Ampere, Recent developments in micromilling using focused ion beam technology. J. Micromech. Microeng. 14(4), R15 (2004). doi:10.1088/0960-1317/14/4/R01
  52. Y. Kim, A.Y. Abuelfilat, S.P. Hoo, A. Al-Abboodi, B. Liu, T. Ng, P. Chan, J. Fu, Tuning the surface properties of hydrogel at the nanoscale with focused ion irradiation. Soft Matter 10(42), 8448–8456 (2014). doi:10.1039/C4SM01061B
  53. A. Minor, in Introduction to Focused Ion Beams: Instrumentation, Theory, Techniques and Practice, ed by L.A. Giannuzzi, F.A. Stevie (Springer, New York, 2005, 27(1), pp. 56–56). ISBN 038723116-1. doi:10.1002/sca.4950270109
  54. T. Hasebe, S. Nagashima, Y. Yoshimoto, A. Hotta, T. Suzuki, Tailoring surface topographies of polymers by using ion beam: recent advances and the potential applications in biomedical and tissue engineering. Nucl. Instrum. Methods Phys. Res., Sect. B 282, 134–136 (2012). doi:10.1016/j.nimb.2011.08.066
  55. M.T. Fitch, J. Silver, CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp. Neurol. 209(2), 294–301 (2008). doi:10.1016/j.expneurol.2007.05.014
  56. W.C. Chang, E. Hawkes, C.G. Keller, D.W. Sretavan, Axon repair: surgical application at a subcellular scale. Wiley interdisciplinary reviews. Nanomed. Nanobiotechn. 2(2), 151–161 (2010). doi:10.1002/wnan.76
  57. M. Lorenzoni, F. Brandi, S. Dante, A. Giugni, B. Torre, Simple and effective graphene laser processing for neuron patterning application. Sci. Rep. 3, 1954 (2013). doi:10.1038/srep01954
  58. N.M. Dowell-Mesfin, M.A. Abdul-Karim, A.M.P. Turner, S. Schanz, H.G. Craighead, B. Roysam, J.N. Turner, W. Shain, Topographically modified surfaces affect orientation and growth of hippocampal neurons. J. Neural Eng. 1(2), 78–90 (2004). doi:10.1088/1741-2560/1/2/003
  59. C. Simitzi, P. Efstathopoulos, A. Kourgiantaki, A. Ranella, I. Charalampopoulos et al., Laser fabricated discontinuous anisotropic microconical substrates as a new model scaffold to control the directionality of neuronal network outgrowth. Biomaterials 67, 115–128 (2015). doi:10.1016/j.biomaterials.2015.07.008
  60. S.I. Nikolaev, A.R. Gallyamov, G.V. Mamin, Y.A. Chelyshev, Poly(epsilon-caprolactone) nerve conduit and local delivery of vegf and fgf2 genes stimulate neuroregeneration. Bull. Exp. Biol. Med. 157(1), 155–158 (2014). doi:10.1007/s10517-014-2513-1
  61. R. Junka, X. Yu, Novel acellular scaffold made from decellularized schwann cell sheets for peripheral nerve regeneration. Regen. Eng. Transl. Med. 1(1), 22–31 (2015). doi:10.1007/s40883-015-0003-2
  62. R.J. McMurtrey, Patterned and functionalized nanofiber scaffolds in three-dimensional hydrogel constructs enhance neurite outgrowth and directional control. J. Neural Eng. 11(6), 066009 (2014). doi:10.1088/1741-2560/11/6/066009
  63. D. Mozaffarian, E.J. Benjamin, A.S. Go, D.K. Arnett, M.J. Blaha et al., Heart disease and stroke statistics—2016 update: a report from the american heart association. Circulation 133(4), 447–454 (2016). doi:10.1161/CIR.0000000000000350
  64. N.M. Malara, V. Trunzo, G. Musolino, S. Aprigliano, G. Rotta et al., Soluble CD54 induces human endothelial cells ex vivo expansion useful for cardiovascular regeneration and tissue engineering application. IJC Heart Vasc. 6, 48–53 (2015). doi:10.1016/j.ijcha.2015.01.004
  65. Y.W. Chun, S.W. Crowder, S.C. Mehl, X. Wang, H. Bae, H.-J. Sung, Therapeutic application of nanotechnology in cardiovascular and pulmonary regeneration. Comput. Struct. Biotechn. J. 7(8), 1–7 (2013). doi:10.5936/csbj.201304005
  66. S. Pagliari, A.C. Vilela-Silva, G. Forte, F. Pagliari, C. Mandoli et al., Cooperation of biological and mechanical signals in cardiac progenitor cell differentiation. Adv. Mater. 23(4), 514–518 (2011). doi:10.1002/adma.201003479
  67. C. Mandoli, F. Pagliari, S. Pagliari, G. Forte, P. Di Nardo, S. Licoccia, E. Traversa, Stem cell aligned growth induced by CeO2 nanoparticles in PLGA scaffolds with improved bioactivity for regenerative medicine. Adv. Funct. Mater. 20(10), 1617–1624 (2010). doi:10.1002/adfm.200902363
  68. P.H. Kim, J.Y. Cho, Myocardial tissue engineering using electrospun nanofiber composites. BMB Rep. 49(1), 26–36 (2016). doi:10.5483/BMBRep.2016.49.1.165
  69. P. Zorlutuna, P. Vadgama, V. Hasirci, Both sides nanopatterned tubular collagen scaffolds as tissue-engineered vascular grafts. J. Tissue Eng. Regen. Med. 4(8), 628–637 (2010). doi:10.1002/term.278
  70. D.A. Stout, J. Yoo, A.N. Santiago-Miranda, T.J. Webster, Mechanisms of greater cardiomyocyte functions on conductive nanoengineered composites for cardiovascular application. Int. J. Nanomed. 7, 5653–5669 (2012). doi:10.2147/IJN.S34574
  71. H. Sun, S. Lu, X.X. Jiang, X. Li, H. Li, Q. Lin, Y. Mou, Y. Zhao, Y. Han, J. Zhou, C. Wang, Carbon nanotubes enhance intercalated disc assembly in cardiac myocytes via the beta1-integrin-mediated signaling pathway. Biomaterials 55, 84–95 (2015). doi:10.1016/j.biomaterials.2015.03.030
  72. V. Martinelli, G. Cellot, F.M. Toma, C.S. Long, J.H. Caldwell et al., Carbon nanotubes promote growth and spontaneous electrical activity in cultured cardiac myocytes. Nano Lett. 12(4), 1831–1838 (2012). doi:10.1021/nl204064s
  73. T. Dvir, B.P. Timko, M.D. Brigham, S.R. Naik, S.S. Karajanagi et al., Nanowired three dimensional cardiac patches. Nat. Nanotechn. 6(11), 720–725 (2011). doi:10.1038/nnano.2011.160
  74. L. Susan, K.C. Casey, R. Seeram, in Nanotechnology and Regenerative Engineering (CRC Press, 2014), pp. 407–434. doi:10.1201/b17444-20
  75. H.N. Chia, B.M. Wu, Recent advances in 3D printing of biomaterials. J. Biol. Eng. 9, 4 (2015). doi:10.1186/s13036-015-0001-4
  76. Z. Karimi, M. Ghorbani, B. Hashemibeni, H. Bahramian, Evaluation of the proliferation and viability rates of nucleus pulposus cells of human intervertebral disk in fabricated chitosan-gelatin scaffolds by freeze drying and freeze gelation methods. Adv. Biomed. Res. 4, 251 (2015). doi:10.4103/2277-9175.170676
  77. J.M. Holzwarth, P.X. Ma, Biomimetic nanofibrous scaffolds for bone tissue engineering. Biomaterials 32(36), 9622–9629 (2011). doi:10.1016/j.biomaterials.2011.09.009
  78. S.-H. Shin, O. Purevdorj, O. Castano, J.A. Planell, H.-W. Kim, A short review: recent advances in electrospinning for bone tissue regeneration. J. Tissue Eng. 3(1), 2041731412443530 (2012). doi:10.1177/2041731412443530
  79. K.M. Tyler, B. Morgan, S. Young-Joon, K. Hyun-Wook, L. Sang Jin, J.Y. James, A. Anthony, A 3D bioprinted complex structure for engineering the muscle–tendon unit. Biofabrication 7(3), 035003 (2015). doi:10.1088/1758-5090/7/3/035003
  80. H. Seitz, W. Rieder, S. Irsen, B. Leukers, C. Tille, Three-dimensional printing of porous ceramic scaffolds for bone tissue engineering. J. Biomed. Mater. Res. B 74(2), 782–788 (2005). doi:10.1002/jbm.b.30291
  81. L.H. Nguyen, N. Annabi, M. Nikkhah, H. Bae, L. Binan, S. Park, Y. Kang, Y. Yang, A. Khademhosseini, Vascularized bone tissue engineering: approaches for potential improvement. Tissue Eng. B 18(5), 363–382 (2012). doi:10.1089/ten.teb.2012.0012
  82. S. Camarero-Espinosa, B. Rothen-Rutishauser, E.J. Foster, C. Weder, Articular cartilage: from formation to tissue engineering. Biomater. Sci. 4, 734–767 (2016). doi:10.1039/C6BM00068A
  83. V.E. Santo, M.E. Gomes, J.F. Mano, R.L. Reis, From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering. Nanomedicine 7(7), 1045–1066 (2012). doi:10.2217/nnm.12.78
  84. G. Tetteh, A.S. Khan, R.M. Delaine-Smith, G.C. Reilly, I.U. Rehman, Electrospun polyurethane/hydroxyapatite bioactive Scaffolds for bone tissue engineering: The role of solvent and hydroxyapatite particles. J. Mech. Behav. Biomed. Mater. 39, 95–110 (2014). doi:10.1016/j.jmbbm.2014.06.019
  85. D. Yuan, Z. Chen, T. Lin, X. Luo, H. Dong, G. Feng, Cartilage tissue engineering using combination of chitosan hydrogel and mesenchymal stem cells. J. Chem. 2015, 530607 (2015). doi:10.1155/2015/530607
  86. B.J. Klotz, D. Gawlitta, A.J.W.P. Rosenberg, J. Malda, F.P.W. Melchels, Gelatin-methacryloyl hydrogels: towards biofabrication-based tissue repair. Trends Biotechn. 34(5), 394–407 (2016). doi:10.1016/j.tibtech.2016.01.002
  87. W. Schuurman, P.A. Levett, M.W. Pot, P.R. van Weeren, W.J.A. Dhert et al., Gelatin-methacrylamide hydrogels as potential biomaterials for fabrication of tissue-engineered cartilage constructs. Macromol. Biosci. 13(5), 551–561 (2013). doi:10.1002/mabi.201200471
  88. K.W.M. Boere, J. Visser, H. Seyednejad, S. Rahimian, D. Gawlitta et al., Covalent attachment of a three-dimensionally printed thermoplast to a gelatin hydrogel for mechanically enhanced cartilage constructs. Acta Biomater. 10(6), 2602–2611 (2014). doi:10.1016/j.actbio.2014.02.041
  89. W. Bian, N. Bursac, Tissue engineering of functional skeletal muscle: challenges and recent advances. IEEE Eng. Med. Biol. Mag. 27(5), 109–113 (2008). doi:10.1109/MEMB.2008.928460
  90. C.A. Rossi, M. Pozzobon, P. De Coppi, Advances in musculoskeletal tissue engineering: moving towards therapy. Organogenesis 6(3), 167–172 (2010). doi:10.4161/org.6.3.12419
  91. D. Klumpp, R.E. Horch, U. Kneser, J.P. Beier, Engineering skeletal muscle tissue–new perspectives in vitro and in vivo. J. Cell Mol. Med. 14(11), 2622–2629 (2010). doi:10.1111/j.1582-4934.2010.01183.x
  92. S. Ostrovidov, V. Hosseini, S. Ahadian, T. Fujie, S.P. Parthiban et al., Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications. Tissue Eng. B 20(5), 403–436 (2014). doi:10.1089/ten.teb.2013.0534
  93. P.Y. Wang, H.T. Yu, W.B. Tsai, Modulation of alignment and differentiation of skeletal myoblasts by submicron ridges/grooves surface structure. Biotechnol. Bioeng. 106(2), 285–294 (2010). doi:10.1002/bit.22697
  94. J.Y. Shen, M.B. Chan-Park, Z.Q. Feng, V. Chan, Z.W. Feng, UV-embossed microchannel in biocompatible polymeric film: application to control of cell shape and orientation of muscle cells. J. Biomed. Mater. Res. B 77(2), 423–430 (2006). doi:10.1002/jbm.b.30449
  95. K.J. Aviss, J.E. Gough, S. Downes, Aligned electrospun polymer fibres for skeletal muscle regeneration. Eur. Cell Mater. 19(1), 193–204 (2010)
  96. L. Altomare, N. Gadegaard, L. Visai, M.C. Tanzi, S. Fare, Biodegradable microgrooved polymeric surfaces obtained by photolithography for skeletal muscle cell orientation and myotube development. Acta Biomater. 6(6), 1948–1957 (2010). doi:10.1016/j.actbio.2009.12.040
  97. M.J. Dalby, Cellular response to low adhesion nanotopographies. Int. J. Nanomed. 2(3), 373–381 (2007)
  98. A.S. Curtis, N. Gadegaard, M.J. Dalby, M.O. Riehle, C.D. Wilkinson, G. Aitchison, Cells react to nanoscale order and symmetry in their surroundings. IEEE Trans. Nanobiosci. 3(1), 61–65 (2004). doi:10.1109/TNB.2004.824276
  99. T.J. Webster, C. Ergun, R.H. Doremus, R.W. Siegel, R. Bizios, Enhanced functions of osteoblasts on nanophase ceramics. Biomaterials 21(17), 1803–1810 (2000). doi:10.1016/S0142-9612(00)00075-2
  100. T.J. Webster, L.S. Schadler, R.W. Siegel, R. Bizios, Mechanisms of enhanced osteoblast adhesion on nanophase alumina involve vitronectin. Tissue Eng. 7(3), 291–301 (2001). doi:10.1089/10763270152044152
  101. R. Murugan, S. Ramakrishna, Design strategies of tissue engineering scaffolds with controlled fiber orientation. Tissue Eng. 13(8), 1845–1866 (2007). doi:10.1089/ten.2006.0078
  102. S. Jana, M. Zhang, Fabrication of 3D aligned nanofibrous tubes by direct electrospinning. J. Mater. Chem. B 1(20), 2575–2581 (2013). doi:10.1039/c3tb20197j
  103. E. Catalano, A. Cochis, E. Varoni, L. Rimondini, B. Azzimonti, Tissue-engineered skin substitutes: an overview. J. Artif. Organs. 16(4), 397–403 (2013). doi:10.1007/s10047-013-0734-0
  104. R. Gupta, D.T. Woodley, M. Chen, Epidermolysis bullosa acquisita. Clin. Dermatol. 30(1), 60–69 (2012). doi:10.1016/j.clindermatol.2011.03.011
  105. V.G. Shalini, N.J. Eric, S.N. Lakshmi, in Nanotechnology and Regenerative Engineering(CRC Press, 2014), pp. 343–366. doi:10.1201/b17444-17
  106. V. Lee, G. Singh, J.P. Trasatti, C. Bjornsson, X. Xu, T.N. Tran, S.-S. Yoo, G. Dai, P. Karande, Design and fabrication of human skin by three-dimensional bioprinting. Tissue Eng. C 20(6), 473–484 (2014). doi:10.1089/ten.tec.2013.0335
  107. R.E. Billingham, J. Reynolds, Transplantation studies on sheets of pure epidermal epithelium and on epidermal cell suspensions. Br. J. Plast. Surg. 5(1), 25–36 (1952). doi:10.1016/S0007-1226(52)80004-9
  108. M.F. Bin Mh Busra, S.R. Chowdhury, F. Bin Ismail, A. Bin Saim, R.H. Idrus, Tissue-engineered skin substitute enhances wound healing after radiation therapy. Adv. Skin Wound Care 29(3), 120–129 (2016). doi:10.1097/01.ASW.0000480556.78111.e4
  109. J. Kober, A. Gugerell, M. Schmid, L.P. Kamolz, M. Keck, Generation of a fibrin based three-layered skin substitute. Biomed. Res. Int. 2015, 170427 (2015). doi:10.1155/2015/170427
  110. F. Wang, M. Wang, Z. She, K. Fan, C. Xu, B. Chu, C. Chen, S. Shi, R. Tan, Collagen/chitosan based two-compartment and bi-functional dermal scaffolds for skin regeneration. Mater. Sci. Eng. C 52, 155–162 (2015). doi:10.1016/j.msec.2015.03.013
  111. Y. Matsumoto, K. Ikeda, Y. Yamaya, K. Yamashita, T. Saito et al., The usefulness of the collagen and elastin sponge derived from salmon as an artificial dermis and scaffold for tissue engineering. Biomed. Res. 32(1), 29–36 (2011). doi:10.2220/biomedres.32.29
  112. I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane, A two-component pre-seeded dermal-epidermal scaffold. Acta Biomater. 10(12), 4928–4938 (2014). doi:10.1016/j.actbio.2014.08.029
  113. S. Rastogi, M. Modi, B. Sathian, The efficacy of collagen membrane as a biodegradable wound dressing material for surgical defects of oral mucosa: a prospective study. J. Oral Maxillofac. Surg. 67(8), 1600–1606 (2009). doi:10.1016/j.joms.2008.12.020
  114. Z. Ghanavati, N. Neisi, V. Bayati, M. Makvandi, The influence of substrate topography and biomaterial substance on skin wound healing. Anat. Cell Biol. 48(4), 251–257 (2015). doi:10.5115/acb.2015.48.4.251
  115. P.T. Hwang, K. Murdock, G.C. Alexander, A.D. Salaam, J.I. Ng, D.J. Lim, D. Dean, H.W. Jun, Poly(epsilon-caprolactone)/gelatin composite electrospun scaffolds with porous crater-like structures for tissue engineering. J. Biomed. Mater. Res. A 104(4), 1017–1029 (2016). doi:10.1002/jbm.a.35614
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